- Author:
- Weiwei Ai <wai484@aucklanduni.ac.nz>
- Date:
- 2025-03-21 14:24:08+13:00
- Desc:
- Update the csv and json files as well
- Permanent Source URI:
- https://staging.physiomeproject.org/workspace/b65/rawfile/cc4effc03581119d92df4eb4fe08eaeb698ea86e/Electrogenic cotransporter/params_kinetic.cellml
<?xml version='1.0' encoding='UTF-8'?>
<model name="params_kinetic" xmlns="http://www.cellml.org/cellml/1.1#" xmlns:cellml="http://www.cellml.org/cellml/1.1#" xmlns:xlink="http://www.w3.org/1999/xlink">
<import xlink:href="./units.cellml">
<units name="C_per_mol" units_ref="C_per_mol"/>
<units name="J_per_K_mol" units_ref="J_per_K_mol"/>
<units name="per_s" units_ref="per_s"/>
<units name="per_s_mM2" units_ref="per_s_mM2"/>
<units name="per_s_mM" units_ref="per_s_mM"/>
<units name="mM" units_ref="mM"/>
<units name="fmol" units_ref="fmol"/>
<units name="fA" units_ref="fA"/>
</import>
<units name="volt_per_s">
<unit exponent="-1" units="second"/>
<unit units="volt"/>
</units>
<component name="params_kinetic">
<variable initial_value="8.31" name="R" public_interface="out" units="J_per_K_mol"/>
<variable initial_value="293" name="T" public_interface="out" units="kelvin"/>
<variable initial_value="96485" name="F" public_interface="out" units="C_per_mol"/>
<variable initial_value="13.7727015449461" name="C_o_0" public_interface="out" units="fmol"/>
<variable initial_value="11.4302815603453" name="C_i_0" public_interface="out" units="fmol"/>
<variable initial_value="72.295598813025" name="CNa2_o_0" public_interface="out" units="fmol"/>
<variable initial_value="1.73527350102727" name="CNa2_i_0" public_interface="out" units="fmol"/>
<variable initial_value="0.16701061319503" name="SCNa2_o_0" public_interface="out" units="fmol"/>
<variable initial_value="0.233806833618937" name="SCNa2_i_0" public_interface="out" units="fmol"/>
<variable name="V0_Vm" public_interface="out" units="volt"/>
<variable initial_value="0.3" name="alpha" public_interface="out" units="dimensionless"/>
<variable initial_value="0.7" name="delta" public_interface="out" units="dimensionless"/>
<variable initial_value="0.08" name="k_12_0" public_interface="out" units="per_s_mM2"/>
<variable initial_value="100" name="k_23_0" public_interface="out" units="per_s_mM"/>
<variable initial_value="50" name="k_34" public_interface="out" units="per_s"/>
<variable initial_value="800" name="k_45" public_interface="out" units="per_s"/>
<variable initial_value="10" name="k_56" public_interface="out" units="per_s"/>
<variable initial_value="3" name="k_61_0" public_interface="out" units="per_s"/>
<variable initial_value="0.3" name="k_25" public_interface="out" units="per_s"/>
<variable initial_value="500" name="k_21_0" public_interface="out" units="per_s"/>
<variable initial_value="20" name="k_32" public_interface="out" units="per_s"/>
<variable initial_value="50" name="k_43" public_interface="out" units="per_s"/>
<variable initial_value="1.0971e4" name="k_54_0" public_interface="out" units="per_s_mM"/>
<variable initial_value="5e-5" name="k_65_0" public_interface="out" units="per_s_mM2"/>
<variable initial_value="35" name="k_16_0" public_interface="out" units="per_s"/>
<variable initial_value="0.823" name="k_52" public_interface="out" units="per_s"/>
<variable initial_value="20" name="Nai" public_interface="out" units="mM"/>
<variable initial_value="100" name="Nao" public_interface="out" units="mM"/>
<variable initial_value="10e-3" name="Glci" public_interface="out" units="mM"/>
<variable initial_value="1e-12" name="Glco" public_interface="out" units="mM"/>
<variable name="t" public_interface="out" units="second"/>
<variable initial_value="-0.05" name="V_E" public_interface="out" units="volt"/>
<variable initial_value="0" name="test_volt" units="volt"/>
<variable name="rate_VE" units="volt_per_s"/>
<variable initial_value="1e-3" name="dt" units="second"/>
<math xmlns="http://www.w3.org/1998/Math/MathML">
<apply>
<eq/>
<ci>V0_Vm</ci>
<ci>V_E</ci>
</apply>
<apply>
<eq/>
<apply>
<diff/>
<bvar>
<ci>t</ci>
</bvar>
<ci>V_E</ci>
</apply>
<ci>rate_VE</ci>
</apply>
<apply>
<eq/>
<ci>rate_VE</ci>
<piecewise>
<piece>
<cn cellml:units="volt_per_s">0</cn>
<apply>
<lt/>
<ci>t</ci>
<cn cellml:units="second" type="e-notation">1204.75<sep/>-3</cn>
</apply>
</piece>
<piece>
<apply>
<divide/>
<apply>
<plus/>
<ci>test_volt</ci>
<cn cellml:units="volt">0.05</cn>
</apply>
<ci>dt</ci>
</apply>
<apply>
<and/>
<apply>
<geq/>
<ci>t</ci>
<cn cellml:units="second" type="e-notation">1204.75<sep/>-3</cn>
</apply>
<apply>
<lt/>
<ci>t</ci>
<apply>
<plus/>
<cn cellml:units="second" type="e-notation">1204.75<sep/>-3</cn>
<ci>dt</ci>
</apply>
</apply>
</apply>
</piece>
<piece>
<cn cellml:units="volt_per_s">0</cn>
<apply>
<and/>
<apply>
<geq/>
<ci>t</ci>
<apply>
<plus/>
<cn cellml:units="second" type="e-notation">1204.75<sep/>-3</cn>
<ci>dt</ci>
</apply>
</apply>
<apply>
<lt/>
<ci>t</ci>
<cn cellml:units="second" type="e-notation">2984.75<sep/>-3</cn>
</apply>
</apply>
</piece>
<piece>
<apply>
<divide/>
<apply>
<minus/>
<apply>
<plus/>
<ci>test_volt</ci>
<cn cellml:units="volt">0.05</cn>
</apply>
</apply>
<ci>dt</ci>
</apply>
<apply>
<and/>
<apply>
<geq/>
<ci>t</ci>
<cn cellml:units="second" type="e-notation">2984.75<sep/>-3</cn>
</apply>
<apply>
<lt/>
<ci>t</ci>
<apply>
<plus/>
<cn cellml:units="second" type="e-notation">2984.75<sep/>-3</cn>
<ci>dt</ci>
</apply>
</apply>
</apply>
</piece>
<otherwise>
<cn cellml:units="volt_per_s">0</cn>
</otherwise>
</piecewise>
</apply>
</math>
</component>
</model>
